منابع مشابه
Cardiovascular pathophysiology of environmental pollutants.
CARDIOVASCULAR DISEASE (CVD) is the leading cause of mortality in the industrialized world. In the United States alone, it kills 1 million people per year; accounting for over 40% of all deaths (50). Despite significant medical advances, the decline in CVD mortality in the United States that began in the 1960s has leveled off, and recent estimates suggest that it may be even beginning to rise a...
متن کاملHeat shock proteins and cardiovascular pathophysiology.
In the eukaryotic cell an intrinsic mechanism is present providing the ability to defend itself against external stressors from various sources. This defense mechanism probably evolved from the presence of a group of chaperones, playing a crucial role in governing proper protein assembly, folding, and transport. Upregulation of the synthesis of a number of these proteins upon environmental stre...
متن کاملRole of platelet-activating factor in cardiovascular pathophysiology.
Platelet-activating factor (PAF) is a phospholipid mediator that belongs to a family of biologically active, structurally related alkyl phosphoglycerides. PAF acts via a specific receptor that is coupled with a G protein, which activates a phosphatidylinositol-specific phospholipase C. In this review we focus on the aspects that are more relevant for the cell biology of the cardiovascular syste...
متن کاملPathophysiology and Implications for Management of Cardiovascular Disease
Case Presentation: E.C. is a 53-year-old postmenopausal female, referred for treatment of hypertension, with a family history of type 2 diabetes, hypertension, and coronary heart disease (CHD). Until learning that her blood pressure was “too high” during a routine physical examination, she felt well, and her postmenopausal symptoms had responded to hormone replacement therapy. She was not overw...
متن کاملPathophysiology of cardiovascular damage in the early renal population.
In renal disease, mechanisms available to compensate for the reduced haemoglobin levels associated with anaemia include increased oxygen extraction from peripheral tissues and, primarily, increased blood flow and changes in blood flow distribution. Haemodynamic changes induced by anaemia include decreases in blood viscosity, peripheral vascular resistance and oxygen delivery, and an increase in...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1988
ISSN: 0021-9746
DOI: 10.1136/jcp.41.7.816-a